ENG polyclonal antibody
产品名称： ENG polyclonal antibody
英文名称： ENG polyclonal antibody
产品编号： PAB11220
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against partial recombinant ENG.
- Immunogen:
- Recombinant protein corresponding to amino acids 26-176 of human ENG.
- Host:
- Rabbit
- Theoretical MW (kDa):
- 95, 190
- Reactivity:
- Human
- Specificity:
- This antibody recognizes 95 KDa for ENG monomer and 190 KDa for ENG dimer.
- Form:
- Liquid
- Purification:
- Immunoaffinity purification
- Concentration:
- Lot specific
- Storage Buffer:
- In 10 mM PBS, pH 7.4 (1% BSA, 0.1% sodium azide)
- Storage Instruction:
- Store at 4°C.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
- Recommend Usage:
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (Formalin/PFA-fixed paraffin-embedded sections) (1:50)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Entrez GeneID:
- 2022
- Gene Name:
- ENG
- Gene Alias:
- CD105,END,FLJ41744,HHT1,ORW,ORW1
- Gene Description:
- endoglin
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds TGFB1 and TGFB3 with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- CD105 antigen,OTTHUMP00000022221,Osler-Rendu-Weber syndrome 1
- Related Disease
- Aneurysm
- Aneurysm, Ruptured
- Arteriovenous Malformations
- Cardiovascular Diseases
- Central Nervous System Vascular Malformations
- Chromosome Aberrations
- Diabetes Mellitus, Type 2
- Edema
- Epistaxis
- Genetic Predisposition to Disease
- Heart Defects, Congenital
- Hypertension, Pulmonary
- Intracranial Aneurysm
- Intracranial Arteriovenous Malformations
- Kidney Failure, Chronic
- Liver Cirrhosis
- Liver Diseases
- Lung Neoplasms
- Pre-Eclampsia