NEFL purified MaxPab rabbit polyclonal antibody (D01P)
产品名称： NEFL purified MaxPab rabbit polyclonal antibody (D01P)
英文名称： NEFL purified MaxPab rabbit polyclonal antibody (D01P)
产品编号： H00004747-D01P
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against a full-length human NEFL protein.
- Immunogen:
- NEFL (NP_006149.2, 1 a.a. ~ 543 a.a) full-length human protein.
- Sequence:
- MSSFSYEPYYSTSYKRRYVETPRVHISSVRSGYSTARSAYSSYSAPVSSSLSVRRSYSSSSGSLMPSLENLDLSQVAAISNDLKSIRTQEKAQLQDLNDRFASFIERVHELEQQNKVLEAELLVLRQKHSEPSRFRALYEQEIRDLRLAAEDATNEKQALQGEREGLEETLRNLQARYEEEVLSREDAEGRLMEARKGADEAALARAELEKRIDSLMDEISFLKKVHEEEIAELQAQIQYAQISVEMDVTKPDLSAALKDIRAQYEKLAAKNMQNAEEWFKSRFTVLTESAAKNTDAVRAAKDEVSESRRLLKAKTLEIEACRGMNEALEKQLQELEDKQNADISAMQDTINKLENELRTTKSEMARYLKEYQDLLNVKMALDIEIAAYRKLLEGEETRLSFTSVGSITSGYSQSSQVFGRSAYGGLQTSSYLMSTRSFPSYYTSHVQEEQIEVEETIEAAKAEEAKDEPPSEGEAEEEEKDKEEAEEEEAAEEEEAAKEESEEAKEEEEGGEGEEGEETKEAEEEEKKVEGAGEEQAAKKKD
- Host:
- Rabbit
- Reactivity:
- Human
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody reactive against mammalian transfected lysate.
- MSDS:
Download
- Publication Reference
- 1.
- Cytoskeletal proteins in the cerebrospinal fluid as biomarker of multiple sclerosis.
Madeddu R, Farace C, Tolu P, Solinas G, Asara Y, Sotgiu MA, Delogu LG, Prados JC, Sotgiu S, Montella A.Neurol Sci. 2012 Feb 24. [Epub ahead of print]
- Applications
- Western Blot (Cell lysate)
- NEFL MaxPab rabbit polyclonal antibody. Western Blot analysis of NEFL expression in Hela NE.
- Protocol Download
- Western Blot (Transfected lysate)
- Western Blot analysis of NEFL expression in transfected 293T cell line (H00004747-T01) by NEFL MaxPab polyclonal antibody.
Lane 1: NEFL transfected lysate(61.50 KDa).
Lane 2: Non-transfected lysate. - Protocol Download
- In situ Proximity Ligation Assay (Cell)
- Proximity Ligation Analysis of protein-protein interactions between NEFL and APP. HeLa cells were stained with anti-NEFL rabbit purified polyclonal 1:1200 and anti-APP mouse monoclonal antibody 1:50. Each red dot represents the detection of protein-protein interaction complex, and nuclei were counterstained with DAPI (blue).
- Entrez GeneID:
- 4747
- GeneBank Accession#:
- NM_006158.2
- Protein Accession#:
- NP_006149.2
- Gene Name:
- NEFL
- Gene Alias:
- CMT1F,CMT2E,FLJ53642,NF-L,NF68,NFL
- Gene Description:
- neurofilament, light polypeptide
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y. [provided by RefSeq
- Other Designations:
- light molecular weight neurofilament protein,neurofilament protein, light chain,neurofilament subunit NF-L,neurofilament triplet L protein,neurofilament, light polypeptide 68kDa,neurofilament-light
- Interactome
- Gene Pathway